Aimee and Lisa are anxious: about germs, about mortality, about the state of the world (and things far less serious, too). Each week they grapple with one of their anxieties, from the trivial to the existential, in a humorous and heartfelt way. They're helped along by smart and entertaining guests like Simon Doonan and Anne Roiphe, who offer advice—and some homework!—for our hosts to overcome their various anxieties.

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