Dr. John Mandrola’s This Week in Cardiology stands out for its combination of critical appraisal of current cardiology literature and his personal opinions. He skillfully analyzes clinical trials, guidelines, and studies, focusing on methodology, biases, and real-world applicability, often challenging mainstream interpretations. I and my colleagues are enjoying to listen his podcast every week! Kudos to Dr. Mandrola and his team for the wonderful work for the cardiology community!

I really appreciate the critical review of current topics in cardiology. A great balance to all of the glowing reports from reps. Thank you.

As an aging cardiologist from the Mayo system, I find this young man’s insights with his summations informative and delightful. His candor is refreshing and objectivity incredibly reassuring. Continue and hold on to your independence. I am a fan. John R

This podcast offers concise and critical reviews of emerging literature in cardiology. I’m very grateful of Dr. Mandrola for committing the time it takes to run such a service.

Absolutely love this podcast and how extraordinarily well Dr Mandrola demonstrates the skill of critical thinking. Always thought provoking

No-nonsense review of current cardiology literature. After many years of listening, I remain a committed fan. After a decade of listening, with each episode Dr. Mandrola continues to take me back to training and feels like my attending imparting wisdom on rounds. Please keep doing the hard work!

Can you do a segment on echo RV strain?

Dr. Mandrola continues to provide an essential voice in cardiology. We need more of his voice and other like him to provide thoughtful review of our field - devoid of misaligned incentives whether they be financial or personal.

Every Saturday morning I look forward to riding my bicycle listening to Dr Mandrola. He brings insights into recent journal articles filtered thru his years of experience and healthy scepticism. I enjoy this podcast above all others.

Thank you John for all you do . I and the two NP’s who I work with are always talking about your podcasts. We particularly respect your perspective on early consideration of palliative care . A Favorite quote from us when discussing treatment options is “ What would John Mandrola say and do” . 😀

The latest trials presented in an easily digestible format, approached with a discerning and practical eye. Discussion often includes critical comparisons to previous studies and how findings may translate to real-life practice. I think of it as a very efficient journal club and try to catch each week’s episode!

I am a CT surgeon and enjoy the podcast. I look forward and listen to the new episode each week. I appreciate the data driven analyses of the contemporary literature. I feel like I have a trusted colleague and expert on my morning drive with me once every week….i wish it were more frequent. Thank you for you work, Dr. Mandrola. You are helping humanity more than you may be aware.

I am an emergency physician who listens to Dr. Mandrola’s weekly podcast. In it he takes an unbiased look at evidence-based cardiology (and other medical topics) eschewing, at times, consensus for what the evidence does or does not suggest. As important, he brings a frank, heart-felt voice to all doctors looking for best practices and solid reasons for why they do what they do. His view is the long view - we are only here temporarily and that duration is unknowable, so make a difference in people’s lives not through professional accolades but who you are as a person. Thank you, Dr. Mandrola, for the humanity you reference and infuse in your weekly podcast.

This presented in a very concise manner without all of the delaying pleasantries and greetings. He gets right to the meat of the topics and gives a great analysis of the data. I learn a lot in a short period of time.

I look forward to each podcast since John takes so much time to critique the articles and not parrot the paper (unlike JACC Podcast). John is truly an iconoclast questioning the validity of published articles. Bravo.

Cardiology fellow here. I love this podcast. I listen to it every week. Great way to stay up to date in a world of so much info/data. Thank you Dr. Mandrola for your efforts.

I’m not a medical professional. At age 60 I decided to educate myself about Americas #1 killer. Over the years I’ve learned the terminology, rarely if ever have to resort to google, and thanks to TWIC should something happen in the future, I won’t sit like a deer in the headlights when a cardiologist while a cardiologist tries to create a “shared decision” protocol while I’m wondering if I live or die … not that I expect this to ever happen … but .. to s5ent or not to stent … that is the question … at least for now … many thanks … I truly enjoy listening to your explanation of the studies. I feel I’ve learned some valuable lessons …

John Madrola’s thoughtful, scientifically rigorous and patient-centered analysis is invaluable in helping me keep abreast with the rapidly evolving data in cardiovascular medicine.

Very informative and helps us truly understand the evidence. Helps us go beyond the noise and tells us the actual evidence behind a medication/procedure!

Dr John Mandrola is the “Man” I have come to listen and appreciate over the last few months. Wonderful insightful look at the evidence and review of trials. You have made me a better cardiologist. Thank you !

The perfect podcast for the most up to date reviews on the latest cardiology trials and news.

He breaks through the hype, smokescreens and data massaging in search of the truth with a patient centric perspective. Highly recommend this for all practicing cardiologists.

Mandrola: Honest critical appraisal based on well considered, fair, informed review of the available information, wrapped in a professional, warm, decent package. I listen and he speaks, yet it feels like a collaborative learning process. And, not unimportantly, all with a polished style and pleasantly listenable voice.

This is the podcast for the cardiologist young or old who is looking to do the right things. Trying to muddle through the advertising and spin and financial incentives for everything we do for people is hard, but I think John Mandrola and his team tries their hardest to do this. It is hard to say we don’t know to patients who want us to know everything. It is hard to say maybe when everyone is saying definitely yes or no. It sounds weak, but it is strong because it is honest. Thank you and your team for doing this work and helping us muddle through more efficiently. I hope you continue this for as long as you all remain passionate about it! It helps so many of us.

Love this podcast! Between you and Dr. Alo's podcast, I should never get heart disease! Thank you!

Thanks for keeping us abreast of the emerging cardiology research trials and keeping a critical eye towards analysis and outcomes. Great bite size podcast to listen on the way home.

Amazing podcast, probably one of the best for critical appraisal of Cardiac literature. Keep up the good fight and holding these trialists and “new fancy devices” to the standards that they should be held to. I love the skepticism and we need more of it, not just in Cardiology.

Great source for information and, most importantly, scientific reflection about trials and debatable conclusions.

I love your thoughtful analysis. I feel led out of Plato‘s cave of industry sponsored group think. Thank you.

Excellent review of the recent literature across the cardiology subspecialties.

Unbelievable enjoyable and thought provoking and professionally gratifying. Your March 13 podcast completely changed my view of this pandemic and humbled me. Thank you.

Enjoy and learn from you every week Can you review lifevests Seems to me to be a lot of expense and hassle Is it worth it Thx

As a nurse practitioner in heart failure, I appreciate the clear-headed and thoughtful breakdown of important studies in the field of cardiology.

I learn something every time! A great review of current papers.

This guy really reads the articles not just the abstracts! What do you think about Ablation as first line for Afib rhythm control?

I stumbled onto the TWIC podcast, liked what I heard, and went back to the beginning and have binged myself to real time. I am a dreaded NP or APC and have never claimed to be anything else. I work in a general cardiology clinic and now see almost exclusively arrhythmia patients. I appreciate the candor with which you share your interpretation (and sometimes opinion) of current studies and practices, topics and trends. I have been in cardiac nursing since the days of quinidine and torsade and strive to remain current with the many changes. Once I thought the ’literature’ was nearly sacrosanct but you have opened my eyes to the possibility of dubious results leading to practice change. Thank you for your time, energy, and contribution to clarity and critical appraisal.

I’m an academic general internist practicing outpatient medicine. Dr. Mandrola gives an evidence-based and rational approach to interpretation of the literature. I gain a lot of insight into the big picture. I appreciate his honesty and balanced view that is not driven by big pharma and the device industry. Kudos! Lenny Mankin, MD, FACP Legacy Health Portland, Oregon

I’m a family practice nurse practitioner and I absolutely love listening to this podcast! Not because it helps me with my everyday practice, but simply because of the way you are walked through critical appraisal of up-to-date trials. Excellent information and I love that you push back against some of the recommendations of modern medicine that may be money makers but not always the best option for health.

I’m a cardiology fellow currently and I almost never miss an episode. The show helps me stay up to date with the newest major trials but most importantly, sets an example of how to critically appraise evidence, to think independently, and to be honest with oneself about the clinical decisions we make. Dr. Mandrola sets an inspirational example with his balanced, humble, and intellectually honest approach to interpreting medical science and practicing evidence based medicine. I’m very grateful for his work and hope he is able to keep this podcast going for many years.

Such a refreshing look at not only research but medicine in general. Dr. Mandrola makes it so easy to follow, it has changed the way I practice!

Mandrola is exceptional with his unbiased reviews and ability to explain complex statistics, even that exhausted cardiologist can understand on the way home after a long day at clinic. He is a master at not only reviewimg the latest in cardiology but has an ability to make it easy and entertaining to listen to. 5 Stars 0 Yawns.

This is a must listen and very relevant to my clinical practice in a busy community hospital

Thank you Dr. Mandrola for the amazing topics you bring up in this podcast. Since started listening to your podcast, I have a different view of some doctors which is very sad.

This podcast is essential listening for practicing cardiologists. The content of this show is superb and is vital to anyone who wishes to practice at the confluence of the best of medical science and experience. Thank you for producing this show; it is a welcome counterpoint to the bloviation common among other medical media.

I’ve been a doctor for 45 years and a cardiologist for 30 years. I now feel I can look at all the information I thought were the absolute virtues in a completely different light. I’ve leant from this podcast that skepticism is and should always be an integral part of scientific research and growth. I am in the medical school again and do enjoy it immensely.

I am an academic cardiologist and I find your show interesting, provocative, and informative. I also agree that exercise should be considered a daily pill!

This podcast is an indispensable resource for all practicing cardiologists. I only wish he would do summaries of all of the evidence for a single topic in one episode. Perhaps that could be his next podcast?

I always appreciate the valuable insight and nuanced understanding you share regarding a variety of cardiology topics. Looking forward to hearing you at the Charleston HFpEF conference this weekend!

In the first 10 minutes of the July 21, 2023 episode Dr. Mandrola discusses potential conflicts of interest between device makers / drug companies and professional societies (MONITOR HF and American College of Cardiology) and ( American Heart Association and Novartis). Entering into these asymmetrical relationships with industry has always compromised the ability of physicians and physician organizations to speak plainly. I appreciate Dr. Mandrola taking a stand on these issues.

Dr. M shows a healthy skeptical but hopeful review of current cardiovascular research. this podcast helps navigate the hodgepodge of ‘research’ out there and brings to the attention of the listener important questions they should be asking themselves about research, the implementation of research into medical practice, and the working of the american medical complex